{"product_id":"histaquel®","title":"HistaQuel®","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eHistaQuel®\u003c\/strong\u003e is a comprehensive formula providing a multi-faceted, systemic approach to supporting healthy mast cell function and histamine response.*\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eWhat is a mast cell?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eMast cells are part of the immune system and are primarily responsible for generating and releasing histamine in the body. Under typical conditions, this is a natural function of a healthy body working to rid itself of an allergen. However, mast cells can become overactive, releasing a cascade of histamine throughout the body, which results in heightened or continuous allergy symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eMany allergy support supplements, such as diamine oxidase (DAO), focus on reducing histamine within the gut by utilizing enzymes to degrade the histamine. Unfortunately, this means they are limited in their function and only effective for reducing ingested histamine (i.e., histamine introduced to the body through the \u003c\/span\u003e\u003ca class=\"editor-rtfLink\" href=\"https:\/\/www.healthline.com\/health\/low-histamine-diet#foods-to-avoid\" rel=\"noopener\" data-mce-fragment=\"1\" data-mce-href=\"https:\/\/www.healthline.com\/health\/low-histamine-diet#foods-to-avoid\" target=\"_blank\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003efood we eat\u003c\/span\u003e\u003c\/a\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003e) within the GI tract. However, mast cells release histamine systemically. Therefore, when mast cells are activated, they release histamine throughout the body. Enzymes such as DAO do nothing to address the healthy function of mast cells or support the body's healthy response to histamine and therefore serve limited benefit.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eHow does HistaQuel® support mast cell health?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eHistaQuel® utilizes a comprehensive approach to support healthy mast cell function and histamine response systemically.* Six clinically researched flavonoids and herbs have been combined to promote healthy levels of histamine production and healthy levels of histamine absorption. This holistic approach resulted in a comprehensive formula featuring dual mechanisms of action.*\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eDual Mechanisms of Action*\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003ePromotes healthy amount of histamine release by supporting healthy mast cell function*\u003c\/span\u003e\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\u003cspan data-preserver-spaces=\"true\" data-mce-fragment=\"1\"\u003eSupports healthy level of histamine absorption by blocking histamine receptors (via competitive inhibition)*\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ctable width=\"1152\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"226\"\u003e\u003cstrong\u003eFeatures\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd width=\"423\"\u003e\u003cstrong\u003eConstituents\/Actions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd width=\"503\"\u003e\u003cstrong\u003eBenefits*\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMast Cell Secure™\u003c\/td\u003e\n\u003ctd\u003eFisetin, Luteolin, Perilla frutescens, Quercefit® Quercetin Phytosome\u003csup\u003e®\u003c\/sup\u003e\n\u003c\/td\u003e\n\u003ctd width=\"503\"\u003e•  Targeted flavonoid blend supports a healthy mast cell release of histamine\u003cbr\u003e•  Moderates interactions between mast cells and activated T cells\u003cbr\u003e•  Supports a healthy Th2 release of allergy promoting cytokines IL-4 and IL-5\u003cbr\u003e•  Supports a healthy IgE mediated release of histamine\u003cbr\u003e•  Highly bioavailable form of Quercetin with 20 times increased absorption compared to standard Quercetin in published research\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHistaCheck™\u003c\/td\u003e\n\u003ctd\u003eStinging Nettle Leaf, Black Cumin (seed) extract\u003c\/td\u003e\n\u003ctd width=\"503\"\u003e•  Promotes a healthy level of histamine to bind to its receptors by competitive inhibition\u003cbr\u003e•  Supports management of a healthy immune system response to allergens\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Researched Nutritionals","offers":[{"title":"Default Title","offer_id":48330338533658,"sku":"RN167","price":35.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0667\/2334\/8762\/files\/HistaQuel_Front.png?v=1712256063","url":"https:\/\/wholesale.inwellbio.com\/products\/histaquel%c2%ae","provider":"InwellBio","version":"1.0","type":"link"}